What causes VILI?

What causes VILI?

CAPILLARY STRESS FAILURE In addition to alveolar epithelial injury, capillary endothelial stress failure likely contributes to VILI. Enhanced regional pulmonary blood flow, such as occurs from hypercapnic adrenergic tone or attempted ventilation-perfusion matching, increases capillary wall stress.

Is ventilator-induced lung injury fatal?

This danger arises from the fact that mechanical ventilation is, first and foremost, a mechanical event; whereas the normal healthy lung is well able to stand the stresses and strains imposed by mechanical ventilation, it can mean irreparable and eventually fatal further damage for the already injured lung.

What is Ergotrauma?

‘ The energy applied to the lung over time must also affect the pulmonary vasculature [4]. Thus, ergotrauma is also a hemodynamic event. One perspective might be that energetic ‘uncoupling’ between the airway and pleural compartments disturbs the pulmonary vasculature by augmenting pulmonary arterial impedance.

Which of the following has been recognized as the classical ventilator-induced lung injury VILI cause?

Classically, VILI has been recognized as the result of high airway forces (high plateau pressure and VT) and modulation of this is now recommended during ventilation for patients with ARDS.

How can ventilator-induced lung injury be prevented?

Implemented almost 2 decades ago, the most important strategy preventing VILI remains ventilation with low tidal volumes (4–8 mL/kg predicted body weight) and low inspiratory pressures (plateau pressure <30 cmH2O).

Can a ventilator cause lung damage?

Ventilator Complications: Lung Damage If the force or amount of air is too much, or if your lungs are too weak, it can damage your lung tissue. Your doctor might call this ventilator-associated lung injury (VALI).