How much do drug-eluting stents cost?
Each drug-eluting coronary stent costs a hospital an average of $2,500, about $1,800 more than the cost of a similar bare-metal stent.
Why is sirolimus used in drug-eluting stents?
Conclusion The use of sirolimus-eluting stents to treat atherosclerotic lesions in small coronary arteries reduces restenosis and may also reduce major adverse cardiac events. Atherosclerotic lesions of small coronary arteries are frequently found in patients undergoing revascularization.
Why are DES drug-eluting stents now used?
A drug-eluting stent is the most common type of stent used to treat a blockage of the heart arteries. Many people with heart problems have been successfully treated with drug-eluting stents, preventing the need for more-invasive procedures, such as coronary artery bypass surgery.
What are the restenosis rates in patients with drug-eluting stents?
High rates of in-stent restenosis (ISR) associated with bare-metal stents (BMSs) led to the development of drug-eluting stents (DESs), which modified the healing process after stent implantation, attenuating neointimal formation, and resulting in a reduction of the incidence of ISR to rates ranging from 5% to 10%.
What are the pros and cons of stents?
The Pros and Cons of Stenting
- A minimally invasive alternative to some cases that would have otherwise required a CABG procedure.
- Long term effect of maintaining proper blood flow in a blood vessel.
- Reduction of the risk of stroke.
- Improvement of organ function, including the kidneys.
When were drug-eluting stents first used?
Eduardo Sousa implanted the first sirolimus-eluting stent in 1999 and it became available for clinical use as CYPHER® (Cordis) stent in 2002.
How can stent restenosis be prevented?
Prevention of in-stent restenosis These strategies are 1) mechanical strategies, 2) systemic drugs, 3) intracoronary radiation, 4) drug-coated and eluting stents, and 5) prospective therapies.