What is a Pituicytoma?
Pituicytoma is a rare tumor of the sellar and suprasellar regions, arising from the pituicytes, which are specialized glial cells in the neurohypophysis and infundibulum. Due to its rarity, ambiguity persists over the diagnosis, management and prognosis of pituicytoma.
What is a Lactotroph adenoma?
INTRODUCTION. Lactotroph adenomas (prolactinomas) usually cause infertility because of the inhibitory effect of elevated prolactin, and sometimes because of the mass effect of a macroadenoma, on gonadotropin secretion, resulting in anovulation and decreased estradiol and progesterone secretion.
WHO classification pituitary tumors?
Abstract. The WHO Classification of Endocrine Tumours designates pituitary neoplasms as adenomas.
What do Pituicytes do?
Pituicytes are similar to astrocytes, another type of glial cell. Their main role is to assist in the storage and release of hormones of the posterior pituitary. Pituicytes surround axonal endings and regulate hormone secretion by releasing their processes from these endings.
What is a granular cell tumor?
Listen to pronunciation. (GRAN-yoo-lur sel TOO-mer) A rare type of soft tissue tumor that usually begins in Schwann cells (cells that hold nerve cells in place). It can occur anywhere in the body, but it usually occurs in or under the skin of the head and neck (especially the mouth or tongue).
What is the histological classification of pituitary Tumours?
Pituitary tumors arise from anterior pituitary cells, most of which are generally benign tumors and are classified as pituitary adenomas (PAs); only 0.1–0.2% of tumors present craniospinal or systemic metastasis, and these tumors are known as pituitary carcinomas (PCs) (1).
How do I know what type of pituitary tumor I have?
How are pituitary tumors diagnosed?
- Blood and urine tests. These tests will check hormone levels in your blood and urine.
- CT scan. This test uses X-rays and a computer to make images of your body.
- MRI.
- Biopsy.
What hormones do Pituicytes produce?
Pituicytes are modified glial cells that reside in the neural lobe of the pituitary, and their movable processes either ensheath or expose nerve terminals that release oxytocin or vasopressin.
What are Acidophils and basophils?
The acidophils secrete GH (somatotropes) and prolactin (mammotropes). Basophils secrete TSH (thyrotropes), LH (gonadotropes), FSH (gonadotropes), and ACTH (corticotropes). The different acidophils and basophils cannot be distinguished in the light microscope.
How is granular cell tumor diagnosed?
The diagnosis of granular cell tumour is made by skin biopsy. Histopathology reveals characteristic granules within the cytoplasm of large tumour cells. A general medical history and examination to exclude any potentially associated conditions are useful.