What is considered a high beta-2 microglobulin level?
Tumor Markers The serum β2-microglobulin level is elevated (>2.7 mg/L) in 75% of patients at the time of diagnosis. Patients with high values have inferior survival. The prognostic value of serum β2-microglobulin levels in myeloma is probably due to two factors: High levels are associated with greater tumor burden.
What are beta 2 proteins?
A small protein normally found on the surface of many cells, including lymphocytes, and in small amounts in the blood and urine. An increased amount in the blood or urine may be a sign of certain diseases, including some types of cancer, such as multiple myeloma or lymphoma.
Is beta globulin the same as beta-2 microglobulin?
Beta globulins are a group of globular proteins in plasma that are more mobile in alkaline or electrically charged solutions than gamma globulins, but less mobile than alpha globulins. Examples of beta globulins include: beta-2 microglobulin.
What is another name for beta-2 microglobulin?
Beta-2 microglobulin
| B2M | |
|---|---|
| Aliases | B2M, entrez:567, IMD43, beta-2-microglobulin, Β2 microglobulin |
| External IDs | OMIM: 109700 MGI: 88127 HomoloGene: 2987 GeneCards: B2M |
| showGene location (Human) | |
| showGene location (Mouse) |
What does a high B2M mean?
People with cancers of the bone marrow and blood often have high levels of B2M in their blood or urine. These cancers include multiple myeloma, lymphoma, and leukemia. High levels of B2M in cerebrospinal fluid can mean that cancer has spread to the brain and/or spinal cord.
Is multiple myeloma curable?
Treatment for multiple myeloma can often help control symptoms and improve quality of life. But myeloma usually can’t be cured, which means additional treatment is needed when the cancer comes back.
What is the survival rate of multiple myeloma?
Survival rates tell you what percentage of people with the same type and stage of cancer are still alive a certain amount of time (usually 5 years) after they were diagnosed….5-year relative survival rates for myeloma.
| SEER stage | 5-year relative survival rate |
|---|---|
| Distant (multiple myeloma) | 55% |
| All SEER stages combined | 56% |